When Grey's Anatomy first premiered in 2005, audiences immediately fell in love with the drama, the new relationships, and Patrick Dempsey's boyish smile along with his fabulous hair. Now, 19 seasons (soon to be 20) later, it comes as no surprise that most of the original cast have left for various reasons. Some wanted to move on in their careers, some butted heads with others on set, and a few respectfully wanted more time to focus on their families. Stream Grey's Anatomy on Netflix and Hulu.
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